Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Adenosine A3 Receptor Agonist, 2-Cl-IB-MECA
A highly selective agonist of adenosine A3 receptor (Ki = 330 pM).
MilliporeSigma™ Calbiochem™ CD45 Inhibitor VI
A cell-permeable, potent, irreversible, non-substrate competitive inhibitor of CD45/PTPRC tyrosine phosphatase activity (IC50 = 290 nM).
MilliporeSigma™ Calbiochem™ (-)-Cytisine
A potent agonist selective for neuronal nAChRs (Ki = 2, 5890, 480, 329, and 492nM at α4β2, α7, α3β4, α6/α4β4, α1β1γδ, respective
MilliporeSigma™ Calbiochem™ PD 168077 Maleate
A selective D4 dopamine receptor agonist (Ki
MilliporeSigma™ Calbiochem™ Hydroxyfasudil
A cell-permeable, hydroxylated metabolite of HA 1077 that displays anti-anginal properties.
MilliporeSigma™ Calbiochem™ MMP-9/MMP-13 Inhibitor I
The MMP-9/MMP-13 Inhibitor I, also referenced under CAS 204140-01-2, controls the biological activity of MMP-9/MMP-13. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ Cytochalasin D, Zygosporium mansonii
Cytochalasin D, Zygosporium mansonii, CAS 22144-77-0, is a fungal toxin that is about 10-fold more potent than cytochalasin B in inhibiting actin filament function. Blocks cytoplasmic division.
MilliporeSigma™ Calbiochem™ Zinc (II) Protoporphyrin IX
A potent and selective inhibitor of heme oxygenase, the enzyme which generates carbon monoxide (CO) and biliverdin.
MilliporeSigma™ Calbiochem™ TGF-β RI Kinase Inhibitor
The TGF-β RI Kinase Inhibitor, also referenced under CAS 396129-53-6, controls the biological activity of TGF-β RI Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Elastase Substrate I, Colorimetric
A specific chromogenic substrate for human neutrophil elastase.
MilliporeSigma™ Calbiochem™ SU1498
A potent, reversible, ATP-competitive and selective inhibitor of Flk-1 kinase (IC50 = 700 nM), a vascular endothelial growth factor (VEGF) receptor kinase.
MilliporeSigma™ Calbiochem™ MK-2 Inhibitor III
The MK-2 Inhibitor III, also referenced under CAS 1186648-22-5, controls the biological activity of MK-2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ RPA Inhibitor, TDRL-505
A cell-permeable compound that targets human Replication Protein A (RPA) and inhibits its DNA-binding activity (IC50 12.9 μM).
MilliporeSigma™ Calbiochem™ ODQ
A cell-permeable, potent and selective inhibitor of nitric oxide (NO)-sensitive guanylyl cyclase (IC50 = 20 nM).
MilliporeSigma™ Calbiochem™ InSolution™ Casein Kinase II Inhibitor I
The InSolution™ Casein Kinase II Inhibitor I controls the biological activity of Casein Kinase II. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.